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LS:Jian Huang

published: 2015-12-10 09:55:23       hits: 

name : Jian Huang Gender: male phone: 028-83202351
email: office-address: Yifu Building 341, Shahe Campus
PH.D  Supervisor: Yes Master Supervisor Yes
major: Biomedical Engineering
research interest: Bioinformatics, Translational Medicine
Biography: Jian Huang holds M.D. degree with experience in medicine, basic immunology and bioinformatics from the West China University of Medical Sciences and the Kyoto University. His studies focus on the molecular aspects and translational applications of antigens, antibodies and peptide aptamers. His work has resulted in the development of a few immunological databases and web programs which have become to be important tools and data resources for both computational biologists and experimental biologists, especially those using phage display technology. Dr. Huang has very close collaborations with bioindustry, which leads to a new drug approved by CFDA. Dr. Huang has also been a reviewer for over 15 peer-reviewed journal and has served as an editor for some of them. In addition, he has served on several scientific advisory panels.
Teaching Schedule: Immunology(Fall)
Bioinformatics Programming Using Perl(Spring)
Selected Publications: 1.Ru B, 't Hoen PAC, Nie F, Lin H, Guo FB, Huang J. PhD7Faster: Predicting clones propagating faster from the Ph.D.-7 phage display peptide library. Journal of Bioinformatics and Computational Biology 2014; 12(1): 1450004.
2.Huang J, Derda R, Huang Y. Phage Display Informatics. Computational and Mathematical Methods in Medicine 2013; 2013: 698395.
3.He B, Mao C, Ru B, Han H, Zhou P, Huang J. Epitope Mapping of Metuximab on CD147 Using Phage Display and Molecular Docking. Computational and Mathematical Methods in Medicine 2013; 2013: 983829.
4.Wu Z, Zhou P, Li X, Wang H, Luo D, Qiao H, Ke X, Huang J. Structural Characterization of a Recombinant Fusion Protein by Instrumental Analysis and Molecular Modeling. PLoS ONE 2013; 8(3): e57642.
5.Zhou P, Wang C, Tian F, Ren Y, Yang C, Huang J. Biomacromolecular quantitative structure-activity relationship (BioQSAR): a proof-of-concept study on the modeling, prediction and interpretation of protein-protein binding affinity. J Comput Aided Mol Des 2013; 27(1): 67-78
6.Huang J, Ru B, Zhu P, Nie F, Yang J, Wang X, Dai P, Lin H, Guo FB, Rao N. MimoDB 2.0: a mimotope database and beyond. Nucleic Acids Research 2012; 40(1): D271-D277.
7.Huang J, Ru B, Dai P. Bioinformatics resources and tools for phage display. Molecules 2011; 16(1): 694-709.
8.Ru B, Huang J, Dai P, Li S, Xia Z, Ding H, Lin H, Guo FB, Wang X. MimoDB: a New Repository for Mimotope Data Derived from Phage Display Technology. Molecules 2010; 15(11): 8279-8288.
9.Huang J, Ru B, Li S, Lin H, Guo F. SAROTUP: Scanner And Reporter Of Target-Unrelated Peptides. Journal of Biomedicine and Biotechnology, 2010; 2010: 101932.
10.Huang J, Honda W, Kanehisa M. Predicting B cell epitope residues with network topology based amino acid indices. Genome Informatics, 2007; 19: 40-49.
11.Huang J, Kawashima S, Kanehisa M. New amino acid indices based on residue network topology. Genome Informatics, 2007; 18: 152-161.
12.Huang J, Gutteridge A, Honda W, Kanehisa M. MIMOX: a web tool for phage display based epitope mapping. BMC Bioinformatics, 2006; 7: 451.
13.Huang J, Honda W. CED: a conformational epitope database. BMC Immunol, 2006; 7: 7.
Books: 1.Huang J, Ru B, Dai P. Prediction of protein interaction sites using mimotope analysis. In: Protein-Protein Interactions -- Computational and Experimental Tools. Edited by Cai W and Hong H. InTech; 2012: 189-206.
2.Huang J, He B, Zhou P. Mimotope-based prediction of B-cell epitopes. Methods in Molecular Biology. 2014; 1184: 237-243.