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LS:Yiyao Liu

published: 2015-12-10 09:57:56       hits: 

name : Yiyao Liu Gender: male phone: 028-83203353
email: office-address:  Main Building Western 222 , ShaHe Campus
PH.D  Supervisor: Yes Master Supervisor Yes
major: Biomedical Enginerring, Biophysics
research interst: Cell biomechanics, Signal transduction, Nanomedicine, Nanoscience, Nano-biomaterials
Biography: Prof. LIU received his Ph.D. degree from the Gunma University of Japan in 2004. He established the Biomechanics and Nanomedicine Lab, UESTC in 2004.He has published more than forthy peer-reviewed papers in international journals. 
Teaching Schedule: Biomechanics and Tissue Engineering (Spring)
Molecular Biology (Fall) 
Selected Publications: 1. Wu C, He Q, Zhu A, Li D, Xu M, Yang H, Liu Y*. (2014) Synergistic anticancer activity of photo- and chemo-responsive nanoformulation based on polylysine-functionalized graphene. ACS Applied Materials & Interfaces. 6(23): 21615-21623.
2. Zhao F, Li L, Guan L, Yang H, Wu C, Liu Y*. (2014) Roles of GP IIb/IIIa and alpha(v)beta(3) integrins in MDA-MB-231 cell invasion and shear flow-induced cancer cell mechanotransduction. Cancer Letters. 344: 62-73;
3. Li L, Zhao F, Lu J, Li T, Yang H, Wu C, Liu Y*. (2014) Notch-1 signaling promotes the malignant features of human breast cancer through NF-kB activation. PLoS One. 9(4): e95912;
4. Yang H, Zhao F, Li Y, Xu M, Li L, Wu C, Miyoshi H, Liu Y*. (2013) VCAM-1-targeted core/shell nanoparticles for selective adhesion and delivery to endothelial cells with lipopolysaccharide-induced inflammation under shear flow and cellular magnetic resonance imaging in vitro. International Journal of Nanomedicine. 8: 1897-1906;
5. Liu Y*, Shi M, Xu M, Yang H, Wu C. (2012) Multifunctional nanoparticles of Fe3O4@SiO2(FITC)/PAH conjugated the recombinant plasmid of pIRSE2-EGFP/VEGF165 with dual functions for gene delivery and cellular imaging. Expert Opinion on Drug Delivery. 9(10): 1197-1207;
6. Yang H, Zhang L, Xiong X, Liu Y*. (2011) Specific adhesion and accumulation of VCAM-1-targeted ultrasound microbubbles to inflammatory endothelial cells under hemodynamic shear flow simulation. Journal of Controlled Release. 152(s1): e227-e229;
7. Shi M, Liu Y*, Xu M, Yang H, Wu C, Miyoshi H. (2011) Core/shell Fe3O4@SiO2 nanoparticles modified with PAH as a vector for EGFP plasmid DNA delivery into HeLa cells. Macromolecular Bioscience. 11: 1563-1569;
8. Yang H, Lou C, Xu M, Wu C, Miyoshi H, Liu Y*. (2011) Investigation of folate conjugated fluorescent silica nanoparticles for targeting delivery to folate receptor-positive tumors and their internalization mechanism. International Journal of Nanomedicine. 6: 2023-2032;
9. Yang H, Xiong X, Zhang L, Wu C, Liu Y*. (2011) Adhesion of bio-functionalized ultrasound microbubbles to endothelial cells by targeting to vascular cell adhesion molecule-1 under shear flow. International Journal of Nanomedicine. 6: 2043-2051;
10. Liu Y*, Lou C, Yang H, Shi M, Miyoshi H. (2011) Silica nanoparticles as potential drug/gene delivery carriers and fluorescent nano-probes: recent advances. Current Cancer Drug Targets. 11: 156-163;
11. Meng G, Liu Y*, Lou C, Yang H. (2010) Emodin suppresses lipopolysaccharide-induced pro-inflammatory responses and NF-kB activation by disrupting lipid rafts in CD14-negative endothelial cells. British Journal of Pharmacology. 161: 1628-1644;
12. Liu Y*, Zhao F, Gu W, Yang HS, Meng Q, Zhang Y, Yang H, Duan Q. (2009) The Roles of Platelet GP IIb/IIIa and alpha(v)beta(3) integrins during HeLa cells adhesion, migration, and invasion to monolayer endothelium under static and dynamic shear flow. Journal of Biomedicine and Biotechnology. doi:10.1155/2009/829243;
13. Miyoshi H,* Matsuo Y, Liu Y*, Sakata T, Mori H. (2009) Behaviors of the fluorescent molecules bound to the interior of the silica nanocapsules in various solvents. Journal of Colloid and Interface Science. 331: 507-513;
14. Liu Y*, Miyoshi H. (2008) Preparation and characterization of novel drug delivery system of light-sensitive silica nanocapsules with thin shells. Journal of Biomedical Nanotechnology. 4: 25-32;
15. Guo Z, Cai SX, Fang R, Chen H, Du J, Tan Y, Ma W, Hu H, Cai SH, Liu Y*. (2007) The synergistic effects of CXCR4 and EGFR on promoting EGF-mediated metastasis in ovarian cancer cells. Colloids and Surfaces B: Biointerfaces. 60: 1-6;
16. Liu Y*, Miyoshi H, Nakamura M. (2007) Nanomedicine for drug delivery and imaging: a promising avenue for cancer therapy and diagnosis by targeted functional nanoparticles. International Journal of Cancer. 120: 2527-2537;
17. Liu Y*, Miyoshi H, Nakamura M. (2007) Novel drug delivery system of hollow mesoporous silica nanocapsules with thin shells: Preparation and fluorescein isothiocyanate (FITC) release kinetics. Colloids and Surfaces B: Biointerfaces. 58: 180-187;
18. Liu Y,* Miyoshi H, Nakamura M. (2006) Encapsulated ultrasound microbubbles: therapeutic application in drug/gene delivery. Journal of Controlled Release. 114: 89-99;
19. Liu Y,* Yang H, Su Q, Sakanishi A. (2006) Influence of parenteral fat emulsion Intralipos and citric acid on blood viscosity and erythrocyte morphology in vitro. Colloids and Surfaces B: Biointerfaces. 53: 51-54;
20. Liu Y*, Yang H, Sakanishi A. (2006) Ultrasound: mechanical gene transfer into plant cells by sonoporation. Biotechnology Advances. 24: 1-16;
21. Liu Y, Uno H, Takatsuki H, Sakanishi A. (2005) Interrelation between HeLa-S3 cell transfection and hemolysis in red blood cell suspension using pulsed ultrasound of various duty cycles. European Biophysics Journal with Biophysics Letters. 34:163-169.