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published: 2015-12-10 10:02:10       hits: 

name : YANG Hong Gender: female phone: 028-83203353
email: office-address:  Main Building middle354 , ShaHe Campus
PH.D  Supervisor: No Master Supervisor Yes
major: Biomedical Enginerring
research interst: Nano-Drug Delivery System, Biomechanics
Biography: Dr. YANG received her Ph.D. degree from the University Electronic Science and Technology of China (UESTC) in 2010. She joined the Biophsics Lab, UESTC in 2004. She has published more than twenty papers. 
Teaching Schedule: Biotechnologyical Pharmaceutics(Spring)
An Introduction to Life Science(Fall) 
Selected Publications: [1] Yang H, Li Y, Chen Y, Wu C, Dong X, Li T, Xu M, Liu Y*. (2014) Multifunctional core/shell nanoparticles cross-linked polyetherimide-folic acid as effecient Notch-1 siRNA carrier for targeted killing of breast cancer. Scientific Reports. 4: 7072, DOI: 10.1038/srep07072
[2] Yang H, Shi M, Xu M, Li Y, Wu C, Liu Y*. (2013) Multifunctional silica nanoparticles as theranostic agents: combining VEGF gene delivery and dual-modality cellular imaging. Journal of Controlled Release. 172(1): e120-e121.
[3] Yang H, Zhao F, Li Y, Xu M, Li L, Wu C, Miyoshi H, Liu Y*. (2013) VCAM-1-targeted core/shell nanoparticles for selective adhesion and delivery to endothelial cells with lipopolysaccharide-induced inflammation under shear flow and cellular magnetic resonance imaging in vitro. International Journal of Nanomedicine. 8: 1897-1906.
[4] Yang H, Zhang L, Xiong X, Liu Y*. (2011) Specific adhesion and accumulation of VCAM-1-targeted ultrasound microbubbles to inflammatory endothelial cells under hemodynamic shear flow simulation. Journal of Controlled Release. 152(s1): e227-e229.
[5] Yang H, Lou C, Xu M, Wu C, Miyoshi H, Liu Y*. (2011) Investigation of folate conjugated fluorescent silica nanoparticles for targeting delivery to folate receptor-positive tumors and their internalization mechanism. International Journal of Nanomedicine. 6: 2023-2032.
[6] Yang H, Xiong X, Zhang L, Wu C, Liu Y*. (2011) Adhesion of bio-functionalized ultrasound microbubbles to endothelial cells by targeting to vascular cell adhesion molecule-1 under shear flow. International Journal of Nanomedicine. 6: 2043-2051.
[7] Yang H, Liu Z, Liu Y*, Lou C, Ren Z, Miyoshi H. (2010) Vascular gene transfer and drug delivery in vitro by using low frequency ultrasound with microbubbles. Acta Pharmacologica Sinca. 31: 515-522.
[8] Yang H, Miyoshi H, Lou C, Ren Z, Liu Y*. (2010) Preparation, characterization and release of methyl viologen from a novel nanoparticle delivery system with double shells of silica and PLGA. Chinese Science Bulletin. 55: 263-267.
[9] Yang H, Li K, Liu Y*, Miyoshi H. (2009) PLGA nanoparticles encapsulated FITC and paclitaxol: preparation, release kinetics and anticancer effect. Journal of Nanoscience and Nanotechnology. 9: 282-287.
[10] Yang H, Liu Y*. (2008) Regulation of calcium signaling during human umbilical vein endothelial cell migration on collagen type I. Biorheology, 45(1-2): 123-124.
[11] Deng L, Li L, Yang H, Li L, Zhao F, Wu C, Liu Y*. (2014) Development and optimization of doxorubicin loaded PLGA nanobubbles for drug delivery into HeLa cells. Journal of Nanoscience and Nanotechnology. 14: 2947-2954.
[12] Zhao F, Li L, Guan L, Yang H, Wu C, Liu Y*. (2014) Roles of GP IIb/IIIa and alpha(v)beta(3) integrins in MDA-MB-231 cell invasion and shear flow-induced cancer cell mechanotransduction. Cancer Letters. 344: 62-73
[13] Li L, Zhao F, Lu J, Li T, Yang, Wu C, Liu Y*. (2014) Notch-1 signaling promotes the malignant features of human breast cancer through NF-kB activation. PLoS ONE. 9: e95912